CYDECTIN Pour-On For Beef and Dairy Cattle: Product Information (Page 2 of 3)

Use Conditions:

Varying weather conditions, including rainfall, do not affect the efficacy of CYDECTIN Pour-On.


CYDECTIN Pour-On is available in three convenient package styles designed for ease of administration and the number of cattle to be treated. Directions for use of each container type follow:

Squeeze-Measure-Pour System
(16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles)

Determine the weight of the animal, calculate the recommended volume of CYDECTIN Pour-On and locate the volume marker equivalent to this dose on the dosing chamber of the bottle. Remove the dosing chamber cap and squeeze the main chamber of bottle until the desired level of solution is present in the dosing chamber. Release pressure on the container to avoid further filling. Holding the dosing chamber as shown below, pour this measured volume of solution evenly along the backline of the animal from the withers to the tailhead (see Figure 1).

Squeeze-Measure-Pour System (16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles)
(click image for full-size original)

Figure 2. Squeeze-Measure Pour System (16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles)

Large Conventional Containers (84.54 fl oz/2.5 L and 169 fl oz/5 L Bottles and 338 fl oz/10 L Cubetainer)

These bottles are designed for use with the CYDECTIN (moxidectin) Pour-On applicators. Simply remove the transient cap and seal and replace with the vented cap. Attach the applicator feeder hose to the vented cap. Invert the container prior to use (2.5 L and 5 L containers only). Apply the recommended volume of CYDECTIN Pour-On evenly along the backline of the animal from the withers to the tailhead (see Figure 1).

Large Conventional Containers 84.54 fl oz/2.5 L and 169 fl oz/5 L Bottles
(click image for full-size original)

Figure 3. Large Conventional Containers (84.54 fl oz/2.5 L and 169 fl oz/5 L Bottles)

Large Conventional Container (338 fl oz/10 L Cubetainer)
(click image for full-size original)

Figure 4. Large Conventional Containers (338 fl oz/10 L Cubetainer)

Animal Safety:

Tolerance and toxicity studies have demonstrated an adequate margin of safety to allow treatment of cattle of all ages with CYDECTIN Pour-On. No toxic signs were seen in cattle given up to 25 times the recommended dose level. Newborn calves similarly showed no toxic signs when treated with up to three times the recommended dose level within 12 hours of birth and nursing from cows concurrently treated with the recommended dose level of CYDECTIN Pour-On. In breeding animals (bulls and cows in estrous and during early, mid and late pregnancy), treatment with three times the recommended dose level had no effect on breeding performance.


Not For Use In Humans. Keep this and all drugs out of the reach of children. This product can cause irritation to skin, eyes, or mucous membranes. In case of accidental skin contact and/or clothing contamination, wash skin thoroughly with soap and water and launder clothing with detergent. In case of accidental eye contact, flush eyes with copious amounts of water. When direct inhalation occurs, cleanse lungs and respiratory passages with fresh air. In case of ingestion do not induce vomiting and seek medical attention immediately. If irritation or any other symptom attributable to exposure to this product persists, consult your physician.

To obtain a copy of the safety data sheet (SDS) which provides more detailed occupational safety information or to report adverse reactions attributable to exposure to this product, call 1-800-422-9874.

Residue Warning:

►When used according to label directions, neither a pre-slaughter drug withdrawal period nor a milk discard time are required. Meat and milk from cattle treated with CYDECTIN (moxidectin) Pour-On may be used for human consumption at any time following treatment. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.◄


Parasite resistance may develop to any dewormer, and has been reported for most classes of dewormers.
Treatment with a dewormer used in conjunction with parasite management practices appropriate to the geographic area and the animal(s) to be treated may slow the development of parasite resistance.
Fecal examinations or other diagnostic tests and parasite management history should be used to determine if the product is appropriate for the herd/ flock, prior to the use of any dewormer. Following the use of any dewormer, effectiveness of treatment should be monitored (for example, with the use of a fecal egg count reduction test or another appropriate method).
A decrease in a drug’s effectiveness over time as calculated by fecal egg count reduction tests may indicate the development of resistance to the dewormer administered. Your parasite management plan should be adjusted accordingly based on regular monitoring.
Macrocyclic lactones provide prolonged drug exposure that may increase selection pressure for resistant parasites. This effect may be more pronounced in extended-release formulations.


For external use only. Do not apply to areas of skin with mange scabs, skin lesions, mud or manure. CYDECTIN Pour-On is not recommended for use in species other than cattle. This product has been formulated specifically for topical use in cattle and should not be used in other animal species or by other routes of administration as adverse reactions may occur.

CYDECTIN Pour-On is effective against the migrating stage of cattle grubs (Hypoderma larvae). Treatment with CYDECTIN Pour-On during the period when grubs are migrating through vital areas may cause undesirable host-parasite reactions. Killing H. lineatum when they are located in peri-esophageal tissues may cause bloat. Killing H. bovis when they are in the vertebral canal may cause staggering or hindlimb paralysis. Cattle should be treated as soon as possible after heel fly (warble fly) season to avoid this potential problem. Cattle treated with CYDECTIN Pour-On at the end of fly season can be re-treated during the winter without danger of grub-related reactions. Consult your veterinarian for more information regarding these secondary grub reactions and the correct time to treat with CYDECTIN Pour-On.

Environmental Safety:

Studies indicate that when moxidectin comes in contact with the soil it readily and tightly binds to the soil and becomes inactive. Free moxidectin may adversely affect fish and certain aquatic organisms. Do not contaminate water by direct application or by improper disposal of drug containers.


Store product at or below room temperature. Avoid prolonged exposure above 25°C (77°F). If product becomes frozen, thaw completely and shake well prior to use.


Dispose of containers in an approved landfill or by incineration.

Package Information:

CYDECTIN Pour-On is available in five convenient container sizes. The 16.91 fl oz/500 mL and 33.81 fl oz/1 L are packaged in specially-designed squeeze-measure-pour polyethylene bottles. When treating larger numbers of cattle, 84.54 fl oz/2.5 L, 169 fl oz/5 L, or 338 fl oz/10 L conventional polyethylene containers are available for use with most commercially-available topical applicators.

U.S. Patent No. 6,514,951

Bayer, the Bayer Cross and Cydectin are registered trademarks of Bayer.

© 2019 Bayer

Restricted Drug (CA) – Use Only As Directed

May, 2019

86921472 LV1905

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